DESARROLLO DE PUPILÓMETRO PORTÁTIL PARA LA CARACTERIZACIÓN DE LA RESPUESTA PUPILAR (DEVELOPMENT OF PORTABLE PUPILLOMETER FOR THE CHARACTERIZATION OF PUPILLARY RESPONSE)
Resumen
El análisis del comportamiento pupilar es una técnica no invasiva que se puede emplear para identificar diversos estados patológicos o psicológicos en una persona, ya que la pupila responde involuntariamente a estímulos lumínicos. Este trabajo presenta el desarrollo de un pupilómetro portátil de bajo costo, basado en una Raspberry Pi, para la medición del comportamiento pupilar ante estímulos luminosos monocromáticos. El dispositivo graba el cambio de diámetro pupilar en tiempo real mediante video, el cual es procesado posteriormente con software en MATLAB para generar la gráfica de la respuesta pupilar, que describe el comportamiento involuntario del ojo ante la luz. A diferencia de los pupilómetros comerciales, este prototipo busca ofrecer una alternativa accesible y económica. Los resultados muestran que el sistema tiene potencial para futuras aplicaciones en la evaluación de la salud ocular y otros estados clínicos. Se describen el hardware utilizado y los resultados preliminares de las pruebas realizadas, así como las expansiones contempladas para el proyecto.
Palabras Clave: Procesamiento de señales, Pupilómetro, Raspberry Pi, Respuesta pupilar, Visión por computadora.
Abstract
Pupillary behavior analysis a non-invasive technique that can be employed to identify certain pathological or psychological states in a person, as the pupil responds involuntarily to light stimuli. This work presents the development of a low-cost portable pupillometer, based on a Raspberry Pi, for measuring pupillary behavior in response to monochromatic light stimuli. The device records real-time changes in pupil diameter via video, which is subsequently processed using MATLAB software to generate a pupillary response graph that describes the involuntary behavior of the eye under light exposure. Unlike commercial pupillometers, this prototype aims to provide an accessible and economical alternative. The results demonstrate the potential of the system for future applications in ocular health assessment and other clinical conditions. The hardware used and preliminary results of the tests are described, as well as the expansions contemplated for the project.
Keywords:Computer vision, Pupillometer, Pupillary response, Raspberry Pi, Signal processing.
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Brown, T. J., Connelly, M., Nichols, C., Neville, A. K. Developmental Changes of Normal Pupil Size and Reactivity in Children. Journal of Pediatric Ophthalmology & Strabismus, Vol. 52, No. 3, 147–151. May, 2015.
El Haj, M., Chapelet, G., Moustafa, A. A., Boutoleau-Bretonnière, C. Pupil size as an indicator of cognitive activity in mild Alzheimer’s disease. Journal of Experimental and Clinical Sciences, Vol. 21, No. 1, 307–316. January, 2022.
Gable, M. T., Kun, L. A., Walker, N. B., Winton, J. R. Comparing Heart Rate and Pupil Size as Objective Measures of Workload in the Driving Context: Initial Look. Adjunct Proceedings of the 7th International Conference on Automotive User Interfaces and Interactive Vehicular Applications, Vol. 1, No. 1, 20–25. September, 2015.
Gabriel, R. L. A., Peachey, S. N., Sunness, S. J. Retinal Function Testing and Genetic Disease. Oxford Monographs on Medical Genetics, No. 2, 343–346, 2012.
Güler, D. A., Ecker, L. J., Lall, S. G., Haq, S., Altimus, M. C., Liao, H., Barnard, R. A., Cahill, H., Badea, C. T., Zhao, H., Hankins, W. M., Berson, M. D., Lucas, J. R., Yau, K., Hattar, S. Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision. Nature, Vol. 453, No. 7191, 102–105. May, 2008.
Hayashi, K., Hyashi, H. Pupil Size Before and After Phacoemulsification in Nondiabetic and Diabetic Patients. Journal of Cataract and Refractive Surgery, Vol. 30, No. 12, 2543–2550. December, 2004.
Herbst, K., Sander, B., Milea, D., Lund-Andersen, H., Kawasaki, A. Test–Retest Repeatability of the Pupil Light Response to Blue and Red Light Stimuli in Normal Human Eyes Using a Novel Pupillometer. Frontiers in Neutology, Vol. 2, No. 1, 1–4. February, 2011.
Howse, J. OpenCV Computer Vision with Python: Learn to Capture Videos, Manipulate Images, and Track Objects with Python Using the OpenCV Library. 1st. Ed. Birmingham: Packt Publ, 41. April, 2013.
Jay, C. B., Karl, C. B., Aleem, I. M., Hari, B., Rockefeller, S. L. Y., Sandra M. B. The Effect of Gender and Iris Color on the Dark-Adapted Pupil Diameter. Journal of Ocular Pharmacology and Therapeutics, Vol. 26, No. 4, 335–340. August, 2010.
Martins da Costa, R., Gonzaga, A. Dynamic Features for Iris Recognition. IEEE Transactions on Systems, Man, Cybern. B, Vol. 42, No. 4, 1072–1082. August, 2012.
Nuske. J. H., Vivanti, G., Hundry, K., Dissanayake, C. Pupillometry Reveals Reduced Unconscious Emotional Reactivity in Autism. Biological Psychology, Vol. 101, No. 1, 24–35. September, 2014.
Silva, G. C. R., Gonçalves, C., Camilo, R. E. N., Boaretti dos Santos, F., Siqueira, J., Simões de Albuquerque, E., Alves de Melo Nunes Soares, F. A., Galdino de Oliveira, L. L., Martins da Costa, R. Automated Evaluation System for Human Pupillary Behavior. International Medical Informatics Association (IMIA) and IOS Press, Vol. 1, No. 1, 589–593. August, 2017.
Wang, C., McInnis, H., Brien, C. D., Pari, G. Disruption of Pupil Size Modulation Correlates with Voluntary Motor Preparation Deficits in Parkinson’s Disease. Neuropsychologia, Vol. 80, No. 1, 176–184. January, 2016. DOI:10.1016/j.neuropsychologia.2015.11.019.
Wang, C., Munoz, P. D. A Circuit for Pupil Orienting Responses: Implications for Cognitive Modulation of Pupil Size. Current Opinion in Neurobiology, Vol. 33, No. 1, 134–140. August, 2015.
Yamaji K., Hiratai Y., Usui, S. The Pupil as a Possible Monitor of the Autonomic Nervous System. Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vol. 1, No. 1, 2777–2781. November, 1997.
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